Overnight stays will be forbidden in northern virus hot spots for four weeks, PM Boris Johnson, will announce tomorrow, according to reports.
It is believed new rules the PM will introduce mean anyone visiting the danger zones will be banned from staying overnight.
Residents will also be asked to leave the highest risk regions for essential travel such as work, education or health reasons, it is claimed.
For the first time Downing Street has confirmed the creation of a new three-tiered system for England called the "Local Covid Alert Levels".
Tier Three is the highest risk – meaning household will not be allowed to mix either indoors or outdoors.
It comes after Mr Johnson last night he told the Cabinet the nation stands at a “critical juncture”.
He also said and more must be done to avoid triggering full lockdowns, The Sun reported.
Tier Three households will not be allowed to mix either indoors or outdoors.
Areas which are thought to have the rules imposed include Liverpool, Manchester and parts of Yorkshire.
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The restrictions are set to be reviewed monthly, The Sun reports.
The country will be placed into "medium", "high" and "very high" alert levels.
There's not yet been any indication which levels will be allocated to which areas of the country. The Government is still "working with local leaders" to determine which regions need the harshest restrictions.
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A Downing Street spokesperson said: "Our primary focus has always been to protect lives and livelihoods while controlling the spread of the virus and these measures will help achieve that aim.
"We must do everything we can to protect the NHS and make sure it can continue to deliver the essential services that so many people rely on.
"This is a critical juncture and it is absolutely vital that everyone follows the clear guidance we have set out to help contain the virus."
The Local Covid Alert Levels system is intended to standardise the current mishmash network of local lockdowns in England so they're easier to understand.
At the moment, more than 50 areas in England are under a confusing array of different lockdown rules.
It comes as the UK grapples with a second wave of Covid-19 infections that could prove to be even worse than the initial outbreak in the spring.
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